NATIONAL: HEALTH & MEDICAL SERVICES, DRUG PATENT: Bengaluru-based firm Synergia Biosciences Develops a nanoemulsion intra-nasal platform for Brain-Related Disorders and gets International Patent

City-based Synergia Biosciences unveiled a nanotechnology-based intra-nasal platform of medicine for brain-related disorders.

It has acquired patents for the same in the United States of America, the European Union, India, and Japan. 

Synergia Biosciences said they have developed the platform in which lipophilic drugs can be dissolved for the intra-nasal spray mode of administering to patient.

“We have patented the composition of the platform and the process to arrive at that,” Sambratha Shetty, Chief Operating Officer, Synergia Biosciences said. 

The nanoemulsion platform presently is best suited to treat various brain-related disorders from cluster headaches, migraine, schizophrenia, dementia, epilepsy, Alzheimer’s and vertigo, binge drinking, depression, among others.

“One of the biggest challenges in drugs treating brain-related disorders is that it is very difficult to make the drug reach the target area. But with the intra-nasal route, it bypasses the first pass metabolism, increases bioavailability of the drug, and causes rapid absorption (less than 5 minutes),” Ms. Shetty explained.

Synergia has stabilised the nanoemulsion for four drugs: two antipsychotic ones, an analgesic, and an antiemetic. The same platform can be tweaked to carry vaccines and insulin, Synergia claimed. 

“The technology is non-invasive and mainly cost-effective. It is an affordable way to treat multiple diseases. This is a strategic technology which will help India treat multiple diseases at an affordable cost,” said Tobby Simon of Synergia Foundation.

source/content: thehindu.com (headline edited)

NATIONAL: INNOVATION: Karnataka Tops NITI Aayog’s ‘India Innovation Index 2022’

Report suggests steps to secure a place in Global Innovation Index’s top 25 nations.

Karnataka has bagged the top rank in NITI Aayog’s India Innovation Index, 2022, which determines innovation capacities and ecosystems at the sub-national level. The State has held this position, under the Major States category, in all three editions of the Index so far.

In the Index released on Thursday, Manipur secured the lead in the Northeast and Hill States category, while Chandigarh was the top performer in the Union Territories and City States category.

Karnataka was followed by Telangana, Haryana, Maharashtra and Tamil Nadu. Chhattisgarh, Odisha, Bihar and Gujarat were at the bottom of the index.

Pointing out that India’s average innovation score is arguably insufficient, given the country’s ambitious targets to be named among the top 25 nations in the Global Innovation Index, the report by the government think tank has recommended measures, such as increasing Gross Domestic Expenditure on R&D (GDERD), promoting private sector participation in R&D and closing the gap between industry demand and what the country produces through its education systems.

The report went on to state that countries that spend less on GDERD fail to retain their human capital in the long run and the ability to innovate is dependent on the quality of human capital; India’s GDERD as a percentage of GDP stood at about 0.7%.

source/content: thehindu.com (headline edited)

INTERNATIONAL: NATIONAL, AVIATION & AEROSPACE: Hindustan Aeronautics Limited (HAL) and Safran Helicopter Engines to Create JV to make Chopper Engines

Hindustan Aeronautics Limited (HAL) and Safran Helicopter Engines have signed an agreement to create a new joint venture to develop helicopter engines. Through an MoU signed by R Madhavan, Chairman & Managing Director, HAL, and Franck Saudo, Chief Executive Officer, Safran Helicopter Engines, in presence of Olivier Andries, CEO, Safran.

Both the partners will extend their partnership by establishing a new aero-engine company in India. It will be dedicated to the development, production, sales and support of helicopter engines and one of its main objectives will be to meet the requirements of HAL and Ministry of Defence’s future heli­copters, including the 13-ton­ne Indian Multi-Role Helicopter.

Madhavan said: “We now look forward to utilize this opportunity to leverage HAL’s experience in manufacturing of more than 15 types of aircraft and helicopter engines to co-develop and manufacture engine with immediate focus on IMRH and its naval variant the Deck Based Multi Role Helicopter. This partnership will involve and utilize the Indian Defence manufacturing ecosystem within India”.

Saudo said the partnership with HAL recently illustrated the development and production of the Shakti engine, “and the inauguration of our joint venture Helicopter Engines MRO Pvt Limited (HE-MRO). With a fleet of over 1,000 engines, India’s Armed Forces are one of the largest operators of Safran-designed helicopter engines.”

HAL and Safran Helicopter Engines already have multiple partnerships, including the Shakti engine, which powers HAL-produced helicopters, including the Dhruv, Rudra and the Light Combat Helicopter. The Ardiden 1U variant also powers the new Light Utility Helicopter. Through HE-MRO joint venture in Goa, HAL and Safran Helicopter Engines will also provide Maintenance, Repair and Overhaul services for TM333 and Shakti engines in se­rvice with Armed Forces, and will be operational by 2023-

source/content: newindianexpress.com (headline edited)

INTERNATIONAL, IN INDIA: KARNATAKA: HEALTH & MEDICAL SERVICES / SCIENCE & TECHNOLOGY: GE Healthcare launches its first ‘5G Innovation Lab’ in India and the First for GE across the Globe.

GE Healthcare on Thursday announced the launch of its 5G Innovation Lab in India, the first for the company across the globe.

With the advantage of massive bandwidth, high data speeds, low latency and highly reliable connectivity, 5G has the potential to disrupt the patient care continuum, transforming diagnosis, therapy, and prognosis, the company noted.

“The 5G Innovation Lab is designed to position GE Healthcare at the forefront of these groundbreaking advances in patient care, including potentially bringing cutting-edge technology to rural and suburban regions,” a company statement said.

Situated at the John F.Welch Technology Centre (JFWTC) Bengaluru, GE Healthcare’s largest R&D centre outside of the USA, the lab will serve as a testbed to develop future-ready products and solutions, turning a new corner in innovation, it said.

5G in Healthcare was valued at an estimated USD 215 million in 2021 and is projected to reach USD 3,667 million by 2026.

“India is an important market for us globally and it is indeed the right time to venture into 5G, which will open a realm of exciting opportunities, driving the next wave of growth in Healthcare,” said Jan Makela, President & CEO, Imaging at GE Healthcare.

The GE Healthcare 5G Innovation Lab will serve as a conduit for the interplay of exponential technologies like AI/ML, IoT, Big Data, Edge Computing and Cybersecurity, the statement added.

source/content: newindianexpress.com (headline edited)

INDIAN RECORDS: KARNATAKA: HEALTH & MEDICAL SCIENCES / SCIENCE & TECHNOLOGY: Researchers at Indian Institute of Science (IISc) Develop Algorithm called (ReAl – LiFE) to Study Connectivity in Brain

Researchers at Indian Institute of Science (IISc.) have developed a new graphic processing unit (GPU) based machine learning algorithm called Regularised, Accelerated, Linear Fascicle Evaluation (ReAl – LiFE), which will help to obtain a better understanding and in the prediction of connectivity between different regions of human brain.

This algorithm can help analyse extensive data generated from diffusion Magnetic Resonance Imaging (dMRI) scans which helps scientists study the connectivity in the brain at a speed, which is 150 times higher than a regular desktop computer or existing state-of-the-art algorithms. The study has been published in the journal Nature Computational Science.

“Even though it is difficult to pinpoint the connectomes, we are trying to infer information highway network by looking at traffic flow patterns (if molecules are like cars). We look at the movement of water molecules in the brain and we try to infer where the wires are. The water molecules have to travel along the length of the cables (axons), which have connected various parts of the brain. By measuring these lengths of water molecules, we are able to infer which areas are connected,” explained Devarajan Sridharan, Associate Professor at the Centre for Neuroscience (CNS), IISc., and corresponding author of the study. 

source/content: thehindu.com (headline edited)

INDIA RECORDS: KARNATAKA: PATENT – SCIENCE & BUILDING TECHNOLOGY: NATIONAL INSTITUTE OF TECHNOLOGY (NIT-K) Surathkal, Faculty Member T. Palaniswamy gets Patent for Producing Cement Mortar Brick having Self-Healing Property upon Cracking

A faculty member at the National Institute of Technology – Karnataka (NIT-K), Surathkal, has received an Indian patent for producing cement mortar brick with inclusion of bacteria in combination.

The brick thus made claims to be superior than the conventional ones in terms of strength and life of the structure and possess a self-healing property.

T. Palanisamy, an assistant professor in the Department of Civil Engineering at the institute, had applied for the patent in 2014 and it was granted in June 2022.

According to Mr. Palanisamy, microbialcreat composite is a new-age material with the property of self-healing upon cracking. This action is by the precipitation of lime (calcium carbonate) by the non-pathogenic bacteria used in the composite, upon coming into contact with air and water through the crack. The precipitated lime will cover the crack, thereby improving the stability of the surface.

source/content: thehindu.com (headline edited)

KARNATAKA RECORDS: Karnataka’s First Intellectual Property Rights (IPR) Cell Inaugurated at JSS Academy of Higher Education and Research (JSS AHER), Mysuru

Focus would be on innovations, research

The JSS Academy of Higher Education and Research in the city in association with the Karnataka State Council for Science and Technology (KSCST) has established an Intellectual Property Rights (IPR) Cell.

It was inaugurated on Thursday and the objectives of the IPR Cell are to strengthen and expand human resources and institutions for training, research, and skill building in Intellectual Property (IP), to raise awareness about IP, catalyse commercialisation of IP, and to promote respect for IP rights.

The authorities said this would be a unique cell as the focus of this IPR cell at JSS AHER would be on innovations, IPR and commercialisation in the health sciences sector, medical devices, and patient care.

K.S.Rangappa, former Vice-Chancellor, University of Mysore, highlighted the importance of scientific research and outcomes in terms of IPR wherein he cited his own example of how out of the 7,000 molecules that he worked on, he could patent 12 products and 2 of these have been commercialised which are generating revenue for the IPR cell of the University of Mysore.

source/content: thehindu.com (headline edited)

INDIA RECORDS : KARNATAKA: SPACE -SATELLITE & LAUNCH VEHICLES: Ananth Technologies opens the Spacecraft Manufacturing unit at KIADB Aerospace Park in City. First Facility in Private Sector.

Ananth Technologies which designs and produces systems for Indian aerospace has set up a 15,000 square metre spacecraft manufacturing unit at KIADB Aerospace Park, Bengaluru, said to be the country’s first such facility in the private sector.

The manufacturing unit would be able to conduct assembly, integration and testing of four large spacecraft simultaneously, the company said in a statement.

Speaking on the occasion, Dr. Subba Rao Pavuluri, Chairman & Managing Director, Ananth Technologies, said, “India is on the cusp of revolutionising the spacecraft industry. As a nation, we are capable of manufacturing world-class spacecrafts.’‘

“Over the years, Ananth Technologies has successfully contributed to major launches of ISRO. Our technology acumen is such that none of the sub-systems supplied by Ananth Technologies has ever failed in orbit,’‘ he claimed.

Since its inception in 1992, Ananth Technologies has contributed to the manufacturing of 89 satellites and 69 launch vehicles built/launched by ISRO, including two satellites for European customers that ISRO had built in collaboration with Airbus, France.

source/content: thehindu.com (edited)

KARNATAKA RECORDS: GREEN ENERGY / TRANSPORT : ElectricPe Aggregates 2,500 EV Charging Points in Bengaluru, Partners with Electric One

To expand its charging infrastructure in Bengaluru and in other parts of India, the company has entered into a partnership with Electric One that has 82 EV super stores across the country.

ElectricPe, an EV charging aggregator platform, claims to have 2,500 public charging points in Bengaluru.

ElectricPe has a B2C EV charging and demand generation app that offers EV users a one-stop platform where users could identify, access, and pay for EV charging points to make e-mobility easier.

ElectricPe has a mandate to facilitate 1,00,000 public charging points across India on its platform by the end of 2022.

source/content: thehindu.com (edited)

INDIA RECORDS: KARNATAKA RECORDS : SOFTWARE & INFORMATION TECHNOLOGY, SECURITY: IISc-Bengaluru Develops Device to Improve Data Encryption

‘This will provide better protection for digital data such as credit card details, password  etc.’

A team at the Department of Electrical Communication Engineering (ECE), Indian Institute of Science (IISc) has developed a true random number generator (TRNG), which, the team says, can improve data encryption and provide improved security for sensitive digital data such as credit card details, passwords and other personal information. The study describing the device has been published in the journal  ACS Nano.

“Almost everything we do on the internet is encrypted for security. The strength of this encryption depends on the quality of random number generation,” explained Nithin Abraham, a PhD student who is a part of a team led by Kausik Majumdar, Associate Professor at ECE, which has developed the device.

Encrypted information can be decoded only by authorised users who have access to a cryptographic ‘key’. But the key needs to be unpredictable and, therefore, randomly generated to resist hacking. Cryptographic keys are typically generated in computers using pseudorandom number generators, which rely on mathematical formulae or pre-programmed tables to produce numbers that appear random but are not. In contrast, a TRNG extracts random numbers from inherently random physical processes, making it more secure, the IISc release explained.

source/content: thehindu.com (edited)