KARNATAKA: INNOVATION – MEDICAL SERVICES / RESEARCH: Detect Diabetes with a Simple Antigen Test, says IISc study

Currently, researchers rely on Radioimmunoassay (RIA) to detect somatostatin levels which use radioactive materials and need to be carried out in labs only.

Detecting diabetes can become as simple as taking a rapid antigen test for Covid-19.  Researchers at the Indian Institute of Science (IISc) have discovered that fluctuations in levels of other hormones such as somatostatin,  secreted by the pancreas, can have a major impact on developing diabetes. 

Scientists argue that usually one gets diagnosed with diabetes when they have high blood glucose levels either because their pancreas does not produce sufficient insulin, or their body cells do not respond to signals from insulin that tell them to use up glucose. This can be avoided by keeping levels of somatostatin in check and potentially detecting diabetes sooner. “Changes in somatostatin secretion can be one of the first signs of diabetes,” said Nikhil Gandasi, Assistant Professor, IISc. 

Somatostatin is secreted by specific cells of the pancreas, called delta cells. “It regulates insulin and glucagon which is another hormone that works hand-in-hand with insulin to maintain blood sugar levels,” said the study.  

Researchers found that when a person is diabetic, their body will secrete less delta cells which means less Somatostatin hormone. The experiment was conducted in pancreatic cells extracted from both mice and humans. The study was published in International Journal of Molecular Sciences called ‘Somatostatin Containing delta-Cell Number Is Reduced in Type-2 Diabetes.’

The team used artificially synthesised somatostatin to test its binding against several commercially available antibodies, in order to identify the one that bound to it most efficiently, which was used to develop the assay.  Similar to the Covid-19 rapid antigen test, the kit works like the standard Enzyme-Linked Immunosorbent Assay that uses antibody-coated plates to identify the presence of antigens in a sample.

Currently, researchers rely on Radioimmunoassay (RIA) to detect somatostatin levels which use radioactive materials and need to be carried out in labs only. “The procedure also takes three days to complete,” said Caroline Miranda, another first author and post-doctoral fellow at the University of Gothenburg.” The new kit will use less blood plasma compared to the RIA method. Researchers are developing the kit into a simple hand-held device that can be mass-produced.   

source/content: newindianexpress.com (headline edited)

KARNATAKA: AGRICULTURE: ‘Cotton Growers’ Convention’ at Agriculture College, Yadgir District

Channappa Anegundi, district president of Karnataka Pranta Raitha Sangha, has said that the cotton growers’ convention at Agriculture College in Bheemarayanagudi, Shahapur taluk of Yadgir district, will be held on Monday.

He was addressing a press conference in Yadgir on Saturday. He said that cotton growers are facing many difficulties majorly the menace of sub-standard sowing seeds. The Centre had failed to take action to prevent such illegal acts. Moreover, the cotton growers have been demand hike in support price. However, the government fixed ₹6,500 per quintal and as a result, many farmers had not sold cotton, waiting for a good price.

Mr. Anegundi said that at the convention, the farmers’ issues will be discussed and a resolution will be passed to take them to the government for immediate solution. Akhila Bharat Kisan Sabha leader Viju Krishnan will take part in the convention and interact with the participants. Around 500 farmers from Kalaburagi, Vijayapur, Raichur, and Yadgir districts are expected to participate.

source/content: thehindu.com (headline edited)

NATIONAL: KARNATAKA: Nilam Kaushik, First Woman Strategy Professor of Indian Institute of Management Bangalore (IIMB) Named among ’40 Best under-40 MBA Professors Worldwide’

She is also the first woman strategy professor at IIMB.

Nilam Kaushik, a strategy professor at Indian Institute of Management Bangalore (IIMB), has become the first faculty member from an Indian business/management school to be named among this year’s ‘Poets and Quants Best 40 under 40 MBA Professors’ worldwide. She is also the first woman strategy professor at IIMB.  

The award, which has been presented for 11 years now, aims to identify and highlight the achievements of the most promising young professors who teach MBA programmes worldwide. Faculty members from 36 different business schools were featured in this year’s list while 16 exceptional women faculty members were honoured.  

“Altogether 1,500 nominations were received this year from students, colleagues, administrators, and faculty themselves. Teaching (both quality and quantity as well as teaching-related awards considered) was assigned a 70% weight and research (volume and impact of the faculty’s scholarly work taken into account, including citations and major media attention as well as research awards and grants) 30% weight,” said a press release from IIMB. 

Sharing that it was an honour to get the recognition, Ms. Kaushik said: “It is a pleasure teaching in a business school where the best of students from across India gain admission through a very rigorous and competitive process.”   

source/content: thehindu.com (headline edited)

KARNATAKA: SPACE TECHNOLOGY: Government’s Visvesvaraya Industrial and Technological Museum (VTU) in Bengaluru Exhibits full-scale replica of Mars Rover Opportunity

The Mars Rover Opportunity model, which was kept as an exhibit at the Visvesvaraya Industrial and Technological Museum, was inaugurated on Thursday.

If you are curious to know how the Mars Rover Opportunity of US space agency NASA, which traversed through the barren land of the red planet and revealed many secrets about it, then head straight to the Space Technology gallery of the Visvesvaraya Industrial and Technological Museum (VITM) here.

The Mars Rover Opportunity model, which was built by the students of Cornell University and kept as exhibit at the VITM, was inaugurated by M Sankaran, Director, UR Rao Satellite Centre of Indian Space Research Organisation on Thursday.

The model was initially on display at the Smithsonian’s Air and Space Museum in Dulles, Virginia, in US, and later exhibited in the US Pavelion during the 2020 World Expo in Dubai.

The replica was then received by the American Centre in the US Consulate in Chennai where it was on display from November 2022 to March 2023 before landing at the VITM.

US Under Secretary of Commerce for International Trade Marisa Lago said, “As the United States and India forge even closer cooperation across critical sectors, space provides yet another example of our partnership, with today’s dedication ceremony serving as a symbol of our mutual commitment.”

US Consul General in Chennai Judith Ravin said the arrival of the full-scale replica of Mars Rover Opportunity in India symbolised the longstanding space technology cooperation between India and the United States.

India is an important partner to the United States in space exploration. Initiated in 2005, the United States and India Civil Space Joint Working Group is the venue for a productive exchange of views and discussion on new and expanded areas for civil space cooperation, she pointed out.

According to Ravin, the civil space dialogue between United States and India is framed around four working groups: Earth sciences, space science and exploration, heliophysics, and human space flight.

“The cooperation between our two countries shows that the technologies developed in support of space exploration have real-world applications that affect all of us, from advancements in telecommunications and satellite navigation to agricultural monitoring and weather forecasting,” she said.

The Mars Rover Opportunity was operated on the red planet from 2004 to 2018. It sent thousands of pictures to its control station.

source/content: hindustantimes.com (headline edited)

NATIONAL / KARNATAKA: SCIENCE & TECHNOLOGY: IISc Researchers Develop Novel Thermal Desalination System

These systems work by heating saltwater, then condensing the resulting vapour to obtain freshwater and can be a possible solution to increase the availability of clean, potable water.

As a possible solution to increase the availability of clean, potable water, Indian Institute of Science (IISc) researchers have developed a novel thermal desalination system which can work using solar energy.

The most common methods for desalination are membrane-based reverse osmosis and thermal desalination. However, both consume a lot of energy.

According to IISc, thermal desalination systems work by heating saltwater and then condensing the resulting vapour to obtain freshwater.

Environment-friendly

“But the energy required for evaporation is usually obtained from either electricity or combustion of fossil fuels. An environmental-friendly alternative is using solar stills in which solar energy is employed to evaporate saltwater in large reservoirs and the vapour that condenses on a transparent roof is collected. However, during condensation, a thin layer of water forms on the roof, reducing the amount of solar energy that can penetrate the reservoir and therefore, the system’s efficiency,” said IISc.

“As an alternative to such solar stills, the IISc team has developed a novel design for a solar-powered desalination unit that is more energy-efficient, cost-effective and portable, making it convenient to set up in areas with limited access to continuous electricity,” said Susmita Dash, Assistant Professor in the Department of Mechanical Engineering and corresponding author of the study which has been published in Desalination.

The setup, designed by Dash and her PhD student Nabajit Deka, comprises a reservoir of saline water, an evaporator, and a condenser enclosed within an insulating chamber to avoid heat losses to the ambient air. Their system works by using solar thermal energy to evaporate a small volume of water imbibed or “wicked” into the evaporator, which has a textured surface. The wicking of liquid into the evaporator takes advantage of the capillary effect of microscale textures.

“This effect allows liquids to be drawn into narrow spaces of a porous material, much like water being absorbed by a sponge. Utilising this approach, instead of heating the entire liquid volume in the reservoir, results in a significant improvement in the system’s energy efficiency,” says Dash.

Works for groundwater too

Apart from seawater, the system can also work with groundwater containing dissolved salts as well as brackish water. It can be adjusted to align with the shifting positions of the sun during the day.

IISc said that the researchers are currently working on scaling up the system and improving its durability, and increasing the volume of drinking water produced, so that it can be deployed for domestic and commercial use.

source/content: thehindu.com (headline edited)

NATIONAL: LANGUAGES: National Training Programme On ‘Basic Indian Sign Language (ISL) at the All India Institute of Speech and Hearing (AIISH), Mysuru May 24-26

Centre for Augmentative and Alternative Communication & Sign Language, All India Institute of Speech and Hearing (AIISH), Mysuru, in collaboration with Indian Sign Language Research and Training Centre (ISLRTC), New Delhi, is organising a 3-day Short-Term Training Prog. on Basic Indian Sign Language  (ISL) from May 24 to 26.

The resource persons are from ISLRTC, New Delhi, an institute focused on ISL teaching and research, under the Ministry of Social Justice and Empowerment, Government of India.

Speech Language Pathologists, Audiologists, Special Educators and students from various parts of the country will participate in the programme.

The programme has been given the status of Continuing Rehabilitation Education (CRE) programme by the Rehabilitation Council of India (RCI).

The inaugural function will be held at 9.30 am in the Seminar Hall of Academic Block, AIISH, Mysuru. K.M. Gayathri, CEO, Zilla Panchayat, Mysuru, will be the chief guest.

B. Elangovan, Principal, JSS Polytechnic for Differently Abled, Mysuru, will be the guest of honour. Prof. M. Pushavathi, Director, AIISH, will preside.

For details, contact  A.R. Keerthi, PRO, AIISH, on Mob: 98441-81080.

source/content: starofmysore.com (headline edited)

KARNATAKA: SCIENCE & TECHNOLOGY: 80th Birthday Of Science Writer S. Ramprasad On May 21

The 80th birthday celebration of Science writer S. Ramprasad, who is also the Founder-President of Karnataka Muktaka Sahitya Academy and the release of four books have been organised by District Kannada Sahitya Parishat, Mysuru, Kannada Sahitya Kalakoota, Mysuru and Hoysala Kannada Sangha, on May 21 at 11 am at Rotary West Auditorium, Saraswathipuram in city.

Suttur Seer Sri Shivarathri Deshikendra Swamiji will grace the occasion. Managing Director of Karnataka State Industrial and Infrastructure Development Corporation Limited (KSIIDC) Dr. M.R. Ravi will release the books and deliver felicitation address.

Litterateur Dr. Kabbinale Vasanth Bharadwaj will speak on the books ‘Ramaprabhe’ and ‘Maneyondu Bagilaidu’ while Karnataka State Open University (KSOU) Kannada Professor Dr. Jyothi Shankar will speak on ‘Kelu Jaana Thammana Muktakagalu’ and ‘Alvars and Sri Ramanujacharya’.

District Kannada Sahitya Parishat President Maddikere Gopal will preside. Kalakoota President M. Chandrashekar will deliver introductory address.

S. Ramprasad will also speak. General Secretary of Hoysala Kannada Sangha Ranganath (of Sushmita Prakashana), Muktaka writer M. Muthuswamy (of Muddukrishna Prakashana) and Editor of ‘Sudharma’ Sanskrit daily Padma Shri K.S. Jayalakshmi will be present, according to a press release.

source/content: starofmysore.com (headline edited)

Tech blog winner’s programme to identify plants may prove a game changer in Ayurvedic pharma sector

Dr K V N Rajesh, a certified trainer on the Azure platform and holds a doctorate in deep learning, says that his model has achieved 95 per cent accuracy in identifying images of leaves available on the internet, based on the plant “flavia”.

With Ayurveda making rapid strides in the Indian pharmaceutical industry, the winning entry by Dr K V N Rajesh in the first phase of the ongoing Microsoft Azure Blogathon contest may prove to bring dynamic change rooted in this direction. The programme, written in the Python programming language and using Microsoft’s Azure cloud platform, is intended to help distinguish between different types of plants.

Rajesh, who is a certified trainer on the Azure platform and holds a doctorate in deep learning, said that there are many species of plants and identifying them based on the leaves is a task that needs to be solved. “Many companies making Ayurvedic products use leaves in their products, and identifying the exact species is a crucial problem,” he says. He also explains that the same concept can be applied in the agricultural field, specifically with regard to dealing with plant diseases and pests.

“Plant leaves have attributes such as colour, shape, texture etc. based on which you can identify them. I developed an architecture based on a deep learning model, a subset of artificial intelligence which will automatically grasp these attributes. The model which is generated is trained with images of leaves. When the model training is complete, it is validated based on the data set of the leaves,” he points out.

The second phase of testing involves testing the accuracy of the model. According to Rajesh, his model has achieved 95 per cent accuracy in identifying images of leaves available on the internet, based on the plant “flavia”.

“Thirty per cent of the images were used to train the model, and the rest were used to test it,” he says. He intends to take the programme further by incorporating it into a mobile application.

source/content: indianexpress.com (headline edited)

NATIONAL: MEDICAL & HEALTH SCIENCES : ‘KMC-EREVNA 2023’, 2-day National Level Medical Undergraduate Conference held in Mangaluru

KMC-EREVNA 2023, a two-day national level medical undergraduate conference was held at Kasturba Medical College on the April 28-29, by the undergraduate students’ research body, Student Research Forum, KMC, Mangaluru under guidance from Dr Priyanka and Dr Deepthi.

The conference comprised of various sessions of scientific paper, poster and case report presentations, ideathon, medical research debate and quiz. Around 300 delegates from across the country participated in the conference.

The inaugural was held on the first day with the lighting of the lamp by chief guest honourable vice chancellor of Manipal Academy of Higher Education, Manipal, Lt Gen Dr M D Venkatesh, pro vice chancellor (Mangaluru campus) Dr Dilip G Naik was the guest of honour.

The dean of KMC Mangalore Dr B Unnikrishnan also spoke and Associate Dean (Research) Dr.Pramod Kumar welcomed the delegates.

The vote of thanks was proposed by vice president of EREVNA Janet. Earlier president of organizing committee Ms.Nishtha gave the opening remarks.

The vice chancellor of Manipal Academy of Higher Education lauded the efforts of the student research forum and had some encouraging words for the entire team and participants.

The valedictory event on the final day saw Dr Ramesh Bhat, vice dean, Father Muller Medical College, as the chief guest and the Raghavendra Subramanya, senior vice president, regional head – Karnataka, DBS Bank was the guest of honour.

The associate dean of research Dr Pramod Kumar and the president of the Student Research Forum, Nishtha Gupta were also present.

Secretary of the conference committee Shruthi proposed the vote of thanks.

source/content: daijiworld.com (headline edited)

INTERNATIONAL & KARNATAKA:SCIENCE & TECHNOLOGY / RESEARCH: Bengaluru and Dresden Researchers Discover Novel Molecular System

Researchers have discovered a novel molecular system that uses alternative chemical energy and employs a novel mechanism to perform mechanical work.

Researchers from Bengaluru and Dresden have discovered a unique two-component molecular motor that uses a kind of renewable chemical energy to pull vesicles toward membrane-bound organelles.

Researchers have discovered a novel molecular system that uses alternative chemical energy and employs a novel mechanism to perform mechanical work.

The researchers, whose work has been published in the journal Nature Physics, are from the National Centre for Biological Sciences (NCBS), the Max Planck Institute of Molecular Cell Biology and Genetics, the Cluster of Excellence Physics of Life and the Biotechnology Center of the Technische Universität Dresden in Dresden, Germany.

Motor proteins are remarkable molecular machines within a cell that converts chemical energy stored in a molecule called ATP, into mechanical work. The most prominent example is myosin which helps our muscles to move.

In contrast, GTPases, which are small proteins, have not been viewed as molecular force generators. One example is a molecular motor composed of two proteins, EEA1 and Rab5, said NCBS.

“Our results show that the proteins EEA1 and Rab5 work together as a two-component molecular motor system that can transfer chemical energy into mechanical work. As a result, they can play active mechanical roles in membrane trafficking. It is possible that the force-generating molecular motor mechanism maybe conserved across other molecules and used by several other cellular compartments,” said Marino Zerial of the Max Planck Institute of Molecular Cell Biology and Genetics.

Overall, the researchers hope that this new interdisciplinary study could open new research avenues in both molecular cell biology and biophysics.

  • Researchers from Bengaluru and Dresden have discovered a unique two-component molecular motor that uses a kind of renewable chemical energy to pull vesicles toward membrane-bound organelles.
  • Motor proteins are remarkable molecular machines within a cell that converts chemical energy stored in a molecule called ATP, into mechanical work. The most prominent example is myosin which helps our muscles to move.
  • In contrast, GTPases, which are small proteins, have not been viewed as molecular force generators. One example is a molecular motor composed of two proteins, EEA1 and Rab5, said NCBS.

source/content: thehindu.com (headline edited)